Posts Tagged "sildenafil"

LSD, MDMA and sildenafil interactions

Posted on Oct 31, 2017 in Doctor X files, Drug interactions

  Is it safe having sildenafil with lsd or mdma pills?     There are no reported cases of severe toxicity mixing MDMA or LSD and sildelnafil. The combination is “probably” (but not “absolutely”) safe. The risk of problems or adverse effects depends on dosage, timing, previous experience with both substances and personal characteristics. It is possible (at least theoretically) some “rebound” effect between vasoconstrictor properties of amphetamines and vasodilator of sildenafil. Moderate dosages of both substances diminish the risk of...

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Multiple questions

Posted on Dec 17, 2016 in Doctor X files, Drug interactions

  i have some questions about some combinations: 1. is it good to use modafinil when using other stimulants (from MDMA to amphetamines)? i use it with depressants (GBL, alcohol) and it works perfectly, but i am not sure if using them with other stimulants does not put too much stress on the brain (i use a lot of antioxidants before, during and after every session with stimultants) 2. i heard that some people use sildenafil/tadalfil to reduce vasoconstriction that some stimulants induce – do you think it is a good idea? also, since alcohol also is a vasodilator would it be good to...

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Cannabis and antiimpotence drugs interactions

Posted on Oct 9, 2016 in Doctor X files, Drug interactions

  Any reason you can think of to avoid the combination of cannabis and one of these drugs sildenafil, vardenafil,¬† or tadalafil? For that matter, any reason you can think of to avoid any or all of the above?     There are no significative interactions described between use of cannabis and PDE-5 inhibitors as sildenafil, tadalafil or vardenafil. Both substances reduce blood pressure and, theoretically use of cannabis under these drugs could enhance this risk. But there are no scientific reports or published cases of this problem so the risk seems unlikely. Poppers are, in fact,...

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