i have some questions about some combinations:

1. is it good to use modafinil when using other stimulants (from MDMA to amphetamines)? i use it with depressants (GBL, alcohol) and it works perfectly, but i am not sure if using them with other stimulants does not put too much stress on the brain (i use a lot of antioxidants before, during and after every session with stimultants)

2. i heard that some people use sildenafil/tadalfil to reduce vasoconstriction that some stimulants induce – do you think it is a good idea? also, since alcohol also is a vasodilator would it be good to use a little alcohol to ease vasoconstriction? (i prefer to use GBL over alcohol since it has less side effects but if this vasodilatation would be worth it i could use it instead)

3. would sildenafil/tadalfil lower blood pressure after stims?

4. good option for person with diabetes to use GHB/GBL? searching on clearnet makes me think yes based on other people reports but just wanted to make sure there is no theoretical reason to worry



  1. Using modafinil in conjunction with stimulants can lead to increased adverse effects stimulant-related.
  2. Sildenafil/tadalafil are selective vasodilators. There is no evidence that they are useful to reduce vasoconstriction induced by drugs
  3. They may do it. But it is not possible to know the exact dosage necessary to lower blood pressure to normal levels. They may cause a “rebound effect” or adverse effects.
  4. On GHB, glucose levels remain stable, unlike alcohol.  From this limited perspective it could be an option for diabetics, although it is important to consider the risks and problems associated with GHB.


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