What would the consequence of using MDMA and Cocaine in the same night be?
The consequences would depend in many factors: timing, total dosage, frequence and personal and environmental factors. In general a variable degree of hyperstimulation could be expected. For most people this is not a pleasant combination, as cocaine reduces empathic effects of MDMA. But it also a matter of personal taste…high dosages of both substances make unpleasant effects (tachicardia, hypertension, anxiety…) more likely