Posts Tagged "amphetamine"

Amphetamine storage

Posted by in Doctor X files, Other drug question

  I usually go to a Techno festival once a year (due to my family situation) or if I were very lucky twice. I always take speed, but due the difficult to find nowadays a good amph, when I find a good batch i buy a little more for the next time, but the next time sometimes is even a year later…..I keep it in the fridge or in the freezer, well packed, Is safe to take it after a year? If the speed lost its properties, what does it mean? its power become low or could it become harmful?     Amphetamine and amphetamine derivatives (meth, MDMA, MDA,2C-X, DO-X…) are simple, stable...

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Rectal drugs administration

Posted by in Doctor X files, Pattern of use

  Is it generally a good idea to stick drugs up your butt? this is a serious question   In general, rectal administration of drugs implies some changes in its distribution and effects. A higher proportion of the drug reaches brain without passing through liver an it produces a faster onset, shorter peak, and shorter duration than the oral route. The absorption can be conditioned by the presence and quantity of faeces in rectum and colon, but in general dosages should be 10-20% lesser than oral route. In moderate use and using hygienic measures risks should not be different to oral route and...

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Amphetamine neurotoxicity

Posted by in Doctor X files, Neurotoxicity

  How long would u have to abuse street-amphetamines (not meth the normal amps) and how often until you damage your neurons ?   Amphetamine can produce neurotoxic effects. There are clear evidences about this both in animals and humans. But it is very difficult to know the toxic dosage and pattern of use. Amphetamine has been used as therapeutic drug up to 40 mg/daily dosage (oral route) without evidence of neurotoxicity in long time. Intranasal or intravenous route probably enhance the possibility of neurotoxicity. The purity (or presence of toxic adulterants) of street amphetamine is...

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MDMA, amphetamines and lactation

Posted by in Doctor X files, Other drug question

  Should MDMA and amphetamines be avoided during lactation? Is it strictly forbidden or risks are acceptable?   The relation between MDMA and lactation is not clear. As far as I know, there are no published studies on this particular issue. Available data on amphetamine show that “In dosages prescribed for medical indications, some evidence indicates that amphetamine might not affect nursing infants adversely.”. On the other hand, data from methamphetamine show that meth is secreted to breast milk and it should be avoided. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2679109/ In...

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Amphetamine and neurotoxicity

Posted by in Doctor X files, Neurotoxicity

  I am prescribed dexedrine and ritalin. Would it be a good idea to combine the two drugs to counteract amphetamine neurotoxicity?   Neurotoxicity of dextroamphetamine is only manifested at very high dosages in some animal models. Dosages used in human prescription are under neurotoxic levels. Methylphenidate (Ritalin) neurotoxic potential is even lower, insignificant, according to studies. http://www.ncbi.nlm.nih.gov/pubmed/9365033 http://www.ncbi.nlm.nih.gov/pubmed/22289608 http://www.ncbi.nlm.nih.gov/pubmed/2440058 So neurotoxicity should not be a matter of concern, considering oral route...

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