I have a question about SSRIs and cocaine. I have been on 100mg of Sertraline (Lustral) since April. I am over the problem that caused me to start this course of medication but plan to stay on it until winter has passed then wean myself off slowly. I know MDMA has little effect whilst on SSRIs so have picked up some high quality cocaine instead. Are there any issues I should be aware of when mixing these two (psychological risks aside)?


Pharmacological interactions are unlikely at that level. No organic complications have been reported by combination of SSRIs and cocaine. Psychological and personal circunstances are the most important issue here.

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